A Chromosome Survey in 71 Couples with Repeated Spontaneous Abortions and Stillbirths

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Chromosomal Analysis of Couples with Repeated Spontaneous Abortions in Northeastern Iran

Background Cytogenetic study of reproductive wastage is an important aspect in determining the genetic background of early embryogenesis. Approximately 15 to 20% of all pregnancies in humans are terminated as recurrent spontaneous abortions (RSAs). The aim of this study was to detect chromosome abnormalities in couples with RSAs and to compare our results with those reported previously. Materia...

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Endometrial Ossification Following Repeated Spontaneous Abortions

Endometrial calcification along with ossification is an uncommon clinical entity. Most of the cases are asymptomatic or present with secondary infertility. Endometrial ossification associated with repeated abortions has been reported very infrequently. Here we report a case of endometrial calcification with ossification  due to retained fetal bony tissue in a 38 year old symptomatic female havi...

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A small supernumerary marker chromosome, derived from chromosome 22, possibly associated with repeated spontaneous abortions.

We report a phenotypically normal couple with repeated spontaneous abortions and without other clinical features. Clinical, hematological, biochemical, and endocrinological aspects of the couple did not reveal any abnormalities. The karyotype of the wife was normal (46,XX), while the husband was found to have an abnormal karyotype, 47,XY,+der(22)mat. The marker chromosome was familial and non-s...

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Relationship between sperm protamine deficiency and apoptosis in couples with unexplained repeated spontaneous abortions

BACKGROUND Etiology of more than half of Recurrent Spontaneous Abortion. The etiology of more than 50 percent of Recurrent Spontaneous Abortions (RSA) cases has been remained unexplained. It is supposed that RSA may have "paternal effect" due to supply 50% of embryonic genomic content by male gamete. OBJECTIVE The aim of present study was to evaluate the role of sperm apoptosis and protamine ...

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Developmental defects and chromosomal aberrations in spontaneous abortions and stillbirths.

The authors analysed 1488 cases of spontaneous abortions and stillbirths in Bratislava. They focused on the course of human embryogenesis and the chromosomal constitution. A high mean frequency rate of both developmental defects (14.4%) and chromosomal aberrations (33.6%) was revealed and both were found to be in close relation with the length of gestation. The most severe developmental defects...

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ژورنال

عنوان ژورنال: Proceedings of the Japan Academy

سال: 1969

ISSN: 0021-4280

DOI: 10.2183/pjab1945.45.180